{"id":1204,"date":"2026-05-21T16:08:55","date_gmt":"2026-05-21T16:08:55","guid":{"rendered":"https:\/\/nexorastudio.ch\/nicomenthyl-test\/wordpress\/?p=1204"},"modified":"2026-05-22T11:56:33","modified_gmt":"2026-05-22T11:56:33","slug":"what-is-the-mechanism-of-action-of-nicomenthyl-20","status":"publish","type":"post","link":"https:\/\/multichem.it\/nicomenthyl\/what-is-the-mechanism-of-action-of-nicomenthyl-20\/","title":{"rendered":"What is the mechanism of action of Nicomenthyl 20?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1204\" class=\"elementor elementor-1204\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7091681 e-con-full e-flex e-con e-parent\" data-id=\"7091681\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-1362393 e-con e-atomic-element e-div-block-base e-1362393-33bafd8 \" data-id=\"1362393\" data-element_type=\"e-div-block\" data-e-type=\"e-div-block\" data-interaction-id=\"1362393\" data-e-type=\"e-div-block\" data-id=\"1362393\">\n    \t\t<div class=\"elementor-element elementor-element-aac0022 elementor-widget elementor-widget-post-info\" data-id=\"aac0022\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-22d5bc3 elementor-inline-item\" itemprop=\"about\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-terms\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-post-info__terms-list\">\n\t\t\t\t<a href=\"https:\/\/multichem.it\/nicomenthyl\/category\/faq-mechanism-action-properties\/\" class=\"elementor-post-info__terms-list-item\">FAQ - Mechanism of action and properties<\/a>\t\t\t\t<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1f35b0f elementor-widget elementor-widget-theme-post-title elementor-page-title elementor-widget-heading\" data-id=\"1f35b0f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"theme-post-title.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">What is the mechanism of action of Nicomenthyl 20?<\/h1>\t\t\t\t<\/div>\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"661fcf7\" data-e-type=\"widget\" data-id=\"661fcf7\">Once absorbed through the skin barrier, Menthyl nicotinate is slowly hydrolysed into its original components: Niacin and Menthol.<br><br>Menthol has a refreshing effect, while Niacin generates a sensation of warmth and enhances skin microcirculation (mild modulated vasodilation). With no irritation or sensitization.<br><br>Furthermore, Niacin triggers a complex cascade of biochemical reactions that produce one of the most important cellular coenzymes, NAD (nicotinamide adenine dinucleotide). NAD plays a pivotal role in hundreds of enzymatic reactions, including those related to energy (ATP) production, many reduction-oxidation metabolic reactions, the Krebs cycle, as well as many others involved in cell signalling within the immune system, DNA repair, epithelial cell renewal, the synthesis of particular lipids (ceramides) essential to skin barrier functionality and integrity.<\/p>\n\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" class=\"e-image-base e-d9c7035-7443f19\" data-interaction-id=\"d9c7035\" data-e-type=\"widget\" data-id=\"d9c7035\" id=\"307\" src=\"https:\/\/multichem.it\/nicomenthyl\/wp-content\/uploads\/2026\/05\/schema-azione.png\" width=\"3720\" height=\"1956\" srcset=\"\" alt=\"\"\/>\t\t\n<\/div>\n\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-19db7946 e-con-full e-flex e-con e-parent\" data-id=\"19db7946\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1f69bb8f elementor-post-navigation-borders-yes elementor-widget elementor-widget-post-navigation\" data-id=\"1f69bb8f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-navigation.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-post-navigation\" role=\"navigation\" aria-label=\"Post Navigation\">\n\t\t\t<div class=\"elementor-post-navigation__prev elementor-post-navigation__link\">\n\t\t\t\t<a href=\"https:\/\/multichem.it\/nicomenthyl\/it\/qual-e-il-meccanismo-dazione-del-nicomenthyl-20\/\" rel=\"prev\"><span class=\"post-navigation__arrow-wrapper post-navigation__arrow-prev\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-angle-left\" viewBox=\"0 0 256 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M31.7 239l136-136c9.4-9.4 24.6-9.4 33.9 0l22.6 22.6c9.4 9.4 9.4 24.6 0 33.9L127.9 256l96.4 96.4c9.4 9.4 9.4 24.6 0 33.9L201.7 409c-9.4 9.4-24.6 9.4-33.9 0l-136-136c-9.5-9.4-9.5-24.6-.1-34z\"><\/path><\/svg><span class=\"elementor-screen-only\">Prev<\/span><\/span><span class=\"elementor-post-navigation__link__prev\"><span class=\"post-navigation__prev--label\">Precedente<\/span><\/span><\/a>\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-post-navigation__separator-wrapper\">\n\t\t\t\t\t<div class=\"elementor-post-navigation__separator\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"elementor-post-navigation__next elementor-post-navigation__link\">\n\t\t\t\t<a href=\"https:\/\/multichem.it\/nicomenthyl\/it\/qual-e-il-tasso-di-incremento-del-microcircolo-cutaneo-prodotto-dal-nicomenthyl-20\/\" rel=\"next\"><span class=\"elementor-post-navigation__link__next\"><span class=\"post-navigation__next--label\">Prossima<\/span><\/span><span class=\"post-navigation__arrow-wrapper post-navigation__arrow-next\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-angle-right\" viewBox=\"0 0 256 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M224.3 273l-136 136c-9.4 9.4-24.6 9.4-33.9 0l-22.6-22.6c-9.4-9.4-9.4-24.6 0-33.9l96.4-96.4-96.4-96.4c-9.4-9.4-9.4-24.6 0-33.9L54.3 103c9.4-9.4 24.6-9.4 33.9 0l136 136c9.5 9.4 9.5 24.6.1 34z\"><\/path><\/svg><span class=\"elementor-screen-only\">Next<\/span><\/span><\/a>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Once absorbed through the skin barrier, Menthyl nicotinate is slowly hydrolysed into its original components: Niacin and Menthol. Menthol has a refreshing effect, while Niacin generates a sensation of warmth and enhances skin microcirculation (mild modulated vasodilation). With no irritation or sensitization. Furthermore, Niacin triggers a complex cascade of biochemical reactions that produce one of [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[44],"tags":[],"class_list":["post-1204","post","type-post","status-publish","format-standard","hentry","category-faq-mechanism-action-properties"],"_links":{"self":[{"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/posts\/1204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/comments?post=1204"}],"version-history":[{"count":4,"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/posts\/1204\/revisions"}],"predecessor-version":[{"id":1821,"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/posts\/1204\/revisions\/1821"}],"wp:attachment":[{"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/media?parent=1204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/categories?post=1204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/multichem.it\/nicomenthyl\/wp-json\/wp\/v2\/tags?post=1204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}