NICOMENTHYL®
(Menthyl nicotinate)
Nicomenthyl is a multifunctional sensorial cosmetic active, derived from Vitamin B3 (Niacin or Nicotinic acid), composed of pure Menthyl nicotinate.
Nicomenthyl® is a registered trademark and a proprietary technology of Multichem R&D.
Fast percutaneous delivery
Rapidly absorbed through the skin barrier and slowly hydrolyzed by esterase.
Skin micro-circulation enhancement
Significantly activates skin microcirculation without causing any unpleasant effect.
Detox & Repair Efficacy
Protective and detoxifying activity against oxidant agents & UV radiations, cigarette smoke & urban dust, blue light & Wi-Fi.
No bothersome "flush"
Simultaneous and time-release delivery of niacin and menthol prevents excessive and bothersome flush.
Carrier effect
Acts as a fixative, carrier and booster for other beneficial lipophilic actives.
NAD-Boosting effect
Very powerful NAD-boosting molecule, and thus instrumental to protect and repair the skin barrier.
Self-emulsifying properties
Being an amphiphilic molecule, supported by appropriate thickening agents, has self-emulsifying properties.
Mechanism of Action
Once absorbed through the horny layer of the skin, Nicomenthyl® is hydrolized by the enzyme esterase and split into its original components: Niacin and Menthol. Menthol is responsible of the cooling sensory effect, while Niacin generates a kind of warming sensation and furthermore triggers the formation of prostaglandins which cause a mild vasodilation and thus a beneficial enhancement of skin microcirculation.
Patent and Certifications
Multichem R&D is proprietary of several patents regarding Menthyl nicotinate.
MENTHYL NICOTINATE SYNTHESIS PROCESS:
US 10,654,806 B2; Europe EP 3 464 241 B1; Italy 102016000058282; Japan 6648311; Korea 10-2159227; Russia 2018146596; China 201780013935.5; India 201817040202.
NICOMENTHYL APPLICATION PATENTS:
COMPOSITIONS AND METHOD FOR THE STIMULATION OF THE FEMALE AND MALE SEXUAL RESPONSE:
US 9,144,572 B2 & Europe EP 2 881 107 B1.