Because it ensures the highest and fastest delivery of Vitamin B3 with no skin irritation or sensitization, as thoroughly documented by several safety and efficacy tests.
Yes, certainly. There is no incompatibility between these two substances.
No, Nicomenthyl 20 is not a whitening agent. On the contrary, it tends to increase cutaneous pigmentation (melanin), while effectively preventing and protecting the skin against UVA and UVB rays damages.
No. Being Niacinamide hydrosoluble, its dermal penetration is hindered by the skin lipid bilayer (hydrophobic) and is not effective enough because it barely permeates the stratum corneum layer of the skin (Sara et al., 2008). From in vivo studies*, the Niacinamide’s absorption rate in 24h is only 2.2% of the initially applied dose, i.e. a very poor amount if compared to the actual quantity of Vitamin B3 released, in 24 hours, through the skin, by Menthyl nicotinate: 18% of the applied dose.
No. Niacinamide, unlike Nicomenthyl 20, has no vasodilating activity, is not a microcirculation enhancer, because it barely permeates the stratum corneum layer of the skin (Sara et al., 2008), and its skin absorption is not effective enough to reach the microcirculation of the dermis, as per the graph shown below.
Niacinamide (also called Nicotinamide), although it is considered another form of Vitamin B3, has a different chemical structure than nicotinic acid. It is a derivative of nicotinic acid, chemically named amide of nicotinic acid:
Niacin or nicotinic acid
They are completely different substances, with completely different molecular structures:
Methyl nicotinate
