Is Niacinamide as easily absorbed by the skin as Nicomenthyl?

No. Since Niacinamide is hydrosoluble, its transcutaneous absorption in 24 hours is only 2.2% of the initially applied dose. Such quantities are very low compared to the amount of Vitamin B3 released by Nicomenthyl (liposoluble) in the same period of time. Such amount reaching a rate of approx. 18% of the Vitamin B3 contained in the applied dose of Nicomenthyl. Therefore, Nicomenthyl delivers approx. 8 times more Vitamin B3 than Niacinamide.