Efficacy and Safety Tests

Is Nicomenthyl 20 a skin irritant?

No. The mild temporary redness that may be observed in some subjects after the application of a cosmetic product containing Nicomenthyl 20 is due to the beneficial activation of the skin microcirculation in the concerned area. Any possible light reddening occurring in sensitive skin will considerably lessen or completely disappear in less than one hour.

Which tests were done to assess the toxicological safety of Nicomenthyl 20?

The following assessment tests were conducted on Nicomenthyl 20: in vitro cutaneous irritation testing on 3D reconstructed human epidermis (according to OCED 439); in vitro model testing to predict skin sensitization through assessment of the stimulating potential of the investigated substance on the immune cellular response mediated by monocyte/macrophage cells; in vitro test method for the prediction of the vaginal tolerability on reconstructed epithelium by means of the viability assessment of reconstructed tissues after single product application; in vitro assessment of the ocular

Has Nicomenthyl 20 been tested on animals?

The founders of Multichem R&D have a strong stand point against animal testing and therefore Nicomenthyl 20 has never been and will never be tested on animals. All testing regulations and requirements by European jurisdiction have been met to ensure Nicomenthyl 20 complete safety and efficacy.